Technology and Drug: Cause Risk factor and Complication of Psoriasis(pa...: Main cause cause of psoriasis isn’t fully known, but it's thought to be related to the immune system and its interaction with the envir...
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Showing posts with label Cause Risk factor and Complication of Psoriasis(part-3). Show all posts
Showing posts with label Cause Risk factor and Complication of Psoriasis(part-3). Show all posts
Cause Risk factor and Complication of Psoriasis(part-3)
Technology and Drug: Cause Risk factor and Complication of Psoriasis(pa...
Technology and Drug: Cause Risk factor and Complication of Psoriasis(pa...: Main cause cause of psoriasis isn’t fully known, but it's thought to be related to the immune system and its interaction with the envir...
Cause Risk factor and Complication of Psoriasis(part-3),
Psoriasis
Cause Risk factor and Complication of Psoriasis(part-3)
Main cause cause of psoriasis isn’t fully known, but it's thought to be related
to the immune system and its interaction with the environment in people
who have the genetic susceptibility. More specifically, one key cell is a
type of white blood cell called a T lymphocyte or T cell. Normally, T
cells travel throughout the body to detect and fight off foreign
substances, such as viruses or bacteria. If you have psoriasis, however,
the T cells attack healthy skin cells by mistake, as if to heal a wound
or to fight an infection.
Overactive T cells trigger other immune responses. The effects include dilation of blood vessels in the skin around the plaques and an increase in other white blood cells that can enter the outer layer of skin. These changes result in an increased production of both healthy skin cells and more T cells and other white blood cells. This causes an ongoing cycle in which new skin cells move to the outermost layer of skin too quickly — in days rather than weeks. Dead skin and white blood cells can't slough off quickly enough and build up in thick, scaly patches on the skin's surface. This usually doesn't stop unless treatment interrupts the cycle.
Just what causes T cells to malfunction in people with psoriasis isn't entirely clear, although researchers think genetic and environmental factors both play a role.
Psoriasis triggers
Psoriasis typically starts or worsens because of a trigger that you may be able to identify and avoid. Factors that may trigger psoriasis include:
Overactive T cells trigger other immune responses. The effects include dilation of blood vessels in the skin around the plaques and an increase in other white blood cells that can enter the outer layer of skin. These changes result in an increased production of both healthy skin cells and more T cells and other white blood cells. This causes an ongoing cycle in which new skin cells move to the outermost layer of skin too quickly — in days rather than weeks. Dead skin and white blood cells can't slough off quickly enough and build up in thick, scaly patches on the skin's surface. This usually doesn't stop unless treatment interrupts the cycle.
Just what causes T cells to malfunction in people with psoriasis isn't entirely clear, although researchers think genetic and environmental factors both play a role.
Psoriasis triggers
Psoriasis typically starts or worsens because of a trigger that you may be able to identify and avoid. Factors that may trigger psoriasis include:
- Infections, such as strep throat or thrush
- Injury to the skin, such as a cut or scrape, bug bite, or a severe sunburn
- Stress
- Cold weather
- Smoking
- Heavy alcohol consumption
- Certain medications — including lithium, which is prescribed for bipolar disorder; high blood pressure medications such as beta blockers; antimalarial drugs; and iodides